Overview

KPV (Lys-Pro-Val) for research use only, is a synthetic tripeptide derived from the C-terminal region of the endogenous peptide hormone alpha-melanocyte stimulating hormone (α-MSH). It has attracted significant interest in peptide research due to its anti-inflammatory properties and activity in a range of preclinical models.

This vial contains 10mg of KPV, supplied lyophilised (freeze-dried), research grade, in a sealed vial. Each batch is independently tested and a batch-specific Certificate of Analysis is published on this page before sale.

KPV is investigated in research settings including inflammatory signalling pathways, gastrointestinal barrier function, epithelial tissue models, and immune system regulation. Velyx makes no health claims about this compound.

What's included

• 1 × KPV 10mg vial — lyophilised, research grade
• Tracked UK delivery

Research use only. Not for human or veterinary consumption. By purchasing you confirm you are 18 or over and understand the research-use-only nature of this product.

Research

Fields of study

KPV appears in peer-reviewed research literature on:

• Inflammatory signalling and cytokine modulation
• Gastrointestinal and intestinal barrier models
• Epithelial tissue research
• Immune system regulation and innate immunity studies
• Mucosal and dermatological inflammation models

Related research — selected papers

• Getting SJ, Schiöth HB, Perretti M. Dissection of the Anti-Inflammatory Effect of the Core and C-Terminal (KPV) α-Melanocyte-Stimulating Hormone Peptides. J Pharmacol Exp Ther. 2003;306(2):631–637. DOI: 10.1124/jpet.103.051623.
• Kannengiesser K, Maaser C, Heidemann J, et al. Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease. Inflamm Bowel Dis. 2008;14(3):324–331. PMID: 18092346. DOI: 10.1002/ibd.20334.
• Dalmasso G, Charrier-Hisamuddin L, Nguyen HTT, et al. PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation. Gastroenterology. 2008;134(1):166–178. DOI: 10.1053/j.gastro.2007.10.026.

Velyx publishes peer-reviewed research citations for context only. No therapeutic claim is made or implied.

Certificates of Analysis

This vial of KPV 10mg is supplied with access to its batch-specific Certificate of Analysis using validated chromatographic and spectrometric techniques. The COA displayed below corresponds to the exact batch you receive.

• KPV 10mg — Batch [insert] — [Download COA PDF — insert link]

Each batch is independently tested for HPLC purity, identity verification, endotoxin (LAL assay), heavy metals (Class 1 and 2), and bioburden (TAMC and TYMC). Velyx does not publish in-house testing in place of independent verification.

COA will be published here before this batch ships.

Preparation & Storage

Reconstitution

This vial arrives lyophilised (freeze-dried powder) and requires reconstitution with bacteriostatic water before use in research.

Storage

• Before reconstitution (lyophilised): refrigerate at 2–8°C. Avoid light. Do not freeze.
• After reconstitution: refrigerate at 2–8°C. Use within 14–30 days.
• In transit: shipped with insulated packaging.

Bacteriostatic water is not included. Available as a Velyx add-on.

All products sold by Velyx Research Ltd are for research purposes only and are not intended for human consumption. By purchasing from this site you confirm that you are 18 or over and understand the research-use-only nature of all products.

Reviews

Verified customer reviews will appear here as orders ship and reviews are submitted. All reviews are post-purchase and unincentivised.